TitleCoarse-grained modelling of DNA and DNA self-assembly
Author(s)Thomas E. Ouldridge
PublicationBerlin, Springer, 2012.
Description1 online resource : ill
Abstract NoteThis thesis presents a novel coarse-grained model of DNA, in which bases are represented as rigid nucleotides. The model is shown to quantitatively reproduce many phenomena, including elastic properties of the double-stranded state, hairpin formation in single strands and hybridization of pairs of strands to form duplexes, the first time such a wide range of properties has been captured by a coarse-grained model. The scope and potential of the model is demonstrated by simulating DNA tweezers, an iconic nanodevice, and a two-footed DNA walker {u2014} the first time that coarse-grained modelling has been applied to dynamic DNA nanotechnology
Notes"Doctoral thesis accepted by the University of Oxford, UK."--T.p. -Includes bibliographical references
Keyword(s)1. DNA 2. EBOOK 3. EBOOK - SPRINGER 4. NANOTECHNOLOGY 5. SCIENCE / Life Sciences / Genetics & Genomics
Item TypeeBook
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